Put simply, no. (Remember, today is April 1st.)
Comic Sans evokes strong feelings. People who know about typography can give you a long list of its failings. What’s more, people who know nothing about the subject get really worked up about it.
Unless you are pulling an April Fool’s prank, best to make another choice.
If you are looking for our REAL, no-foolin’, thoughts on fonts and typography, check out these posts from a few of our designers: